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Clin. Vaccine Immunol. doi:10.1128/CVI.00088-08
Copyright (c) 2008, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Development and characterization of an equine infectious anemia virus Env pseudotyped reporter virus

Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164, USA; Department of Microbiology, University of Iowa, Iowa City, IA 52242, USA

^* To whom correspondence should be addressed. Email: scarp{at}vetmed.wsu.edu.

	Abstract

We developed a replication-defective reporter virus pseudotyped with the envelope glycoprotein of equine infectious anemia virus (EIAV). The in vitro host range and neutralization phenotype of EIAV-Env pseudotyped virus were similar to replication-competent virus. An EIAV-Env pseudovirus will improve antigenic characterization of viral variants and evaluation of lentivirus vaccines.