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Clinical and Vaccine Immunology, September 2009, p. 1366-1368, Vol. 16, No. 9
1071-412X/09/$08.00+0     doi:10.1128/CVI.00204-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Rapid Detection of Vaginal Candida Species by Newly Developed Immunochromatography{triangledown} ,{dagger}

Hidehito Matsui,1 Hideaki Hanaki,1* Kengo Takahashi,2 Akihiko Yokoyama,2 Taiji Nakae,1 Keisuke Sunakawa,3 and Satoshi Omura1,3

Laboratory for Antimicrobial Agents, Kitasato University, 5-9-1 Shirokane, Minato-Ku, Tokyo 108-8641, Japan,1 Isehara Research Laboratory, Kanto Chemical Co., Inc., 21 Suzukawa, Isehara, Kanagawa 259-1146, Japan,2 Graduate School for Infection Control Sciences, Kitasato University, 5-9-1 Shirokane, Minato-Ku, Tokyo 108-8641, Japan3

Received 13 May 2009/ Returned for modification 22 June 2009/ Accepted 23 July 2009

For the diagnosis of vulvovaginal candidiasis, we developed a simple immunochromatographic method that enables the detection of vaginal Candida spp. within about 30 min. Overall, the sensitivity, specificity, positive predictive value, and negative predictive value of this method appeared to be 80.3, 99.3, 98.0, and 92.0%, respectively.

* Corresponding author. Mailing address: Laboratory for Antimicrobial Agents, Kitasato University, 5-9-1 Shirokane, Minato-Ku, Tokyo 108-8641, Japan. Phone: 81-3-5791-6413. Fax: 81-3-5791-6415. E-mail: hanaki{at}insti.kitasato-u.ac.jp

{triangledown} Published ahead of print on 5 August 2009.

{dagger} Supplemental material for this article may be found at http://cvi.asm.org/.

Clinical and Vaccine Immunology, September 2009, p. 1366-1368, Vol. 16, No. 9
1071-412X/09/$08.00+0     doi:10.1128/CVI.00204-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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