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 Previous Article

Clinical and Vaccine Immunology, June 2009, p. 959-961, Vol. 16, No. 6
1071-412X/09/$08.00+0     doi:10.1128/CVI.00262-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Expression of Interleukin-5 and Tumor Necrosis Factor Alpha in Cervical Carcinoma{triangledown}

Dae Woo Lee,1 Young Tae Kim,1* Sang Wun Kim,1 SungHoon Kim,1 Jae Hoon Kim,1 Myung Hwa Kang,1 Jeong Hye Hwang,1 and Jong baeck Lim2

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Yonsei University College of Medicine, Seoul, South Korea,1 Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, South Korea2

Received 18 July 2008/ Returned for modification 12 October 2008/ Accepted 7 April 2009

Interleukin-5 (IL-5) levels were significantly higher in vaginal washing fluids from patients with cervical carcinoma than in those from patients with carcinoma in situ and controls. Tumor necrosis factor alpha levels did not differ among the three groups. Detection of IL-5 in cervical secretions may be a useful marker for evaluating aggressive local immune response in cervical carcinoma.


* Corresponding author. Mailing address: Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun-gu, Seoul 120-752, South Korea. Phone: 82 2 2228 2230. Fax: 82 2 313 8357. E-mail: ytkchoi{at}yuhs.ac

{triangledown} Published ahead of print on 15 April 2009.


Clinical and Vaccine Immunology, June 2009, p. 959-961, Vol. 16, No. 6
1071-412X/09/$08.00+0     doi:10.1128/CVI.00262-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.