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Clinical and Vaccine Immunology, March 2009, p. 423-426, Vol. 16, No. 3
1071-412X/09/$08.00+0     doi:10.1128/CVI.00009-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Detection of (1->3)-β-D-Glucan as an Adjunct to Diagnosis in a Mixed Population with Uncommon Proven Invasive Fungal Diseases or with an Unusual Clinical Presentation{triangledown}

María Soledad Cuétara,1 Almudena Alhambra,2 María Dolores Moragues,3 Ernesto González-Elorza,3 José Pontón,4* and Amalia del Palacio2

Servicio de Microbiología, Hospital Severo Ochoa, Leganés, Madrid,1 Unidad de Micología, Departamento de Microbiología, Hospital Universitario 12 de Octubre, Madrid,2 Departamento de Enfermería I, Universidad del País Vasco, Lejona, Vizcaya,3 Departamento de Inmunología, Microbiología y Parasitología, Facultad de Medicina y Odontología, Universidad del País Vasco, Lejona, Vizcaya, Spain4

Received 15 September 2008/ Accepted 13 January 2009

This single-center observational prospective study evaluated the performance of (1->3)-β-D-glucan as an adjunct diagnostic tool in 12 patients with proven invasive fungal disease with different risk factors. The infections were due to either uncommon fungal pathogens such as dematiaceous molds (Scedosporium apiospermum, Alternaria infectoria, and Cladosporium macrocarpum) and hyaline septate molds (Fusarium solani and Blastoschizomyces capitatus) or Aspergillus spp. with unusual clinical presentations.

* Corresponding author. Mailing address: Departamento de Inmunología, Microbiología y Parasitología, Facultad de Medicina y Odontología, Universidad del País Vasco, Apartado 699, E-48080 Bilbao, Vizcaya, Spain. Phone: 94-601-2855. Fax: 94-601-3495. E-mail: jose.ponton{at}ehu.es

{triangledown} Published ahead of print on 21 January 2009.

Clinical and Vaccine Immunology, March 2009, p. 423-426, Vol. 16, No. 3
1071-412X/09/$08.00+0     doi:10.1128/CVI.00009-09
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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