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Clinical and Vaccine Immunology, July 2008, p. 1128-1131, Vol. 15, No. 7
1071-412X/08/$08.00+0     doi:10.1128/CVI.00085-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Rapid and Simple Diagnosis of Chlamydophila pneumoniae Pneumonia by an Immunochromatographic Test for Detection of Immunoglobulin M Antibodies{triangledown}

Naoyuki Miyashita,1* Kazunobu Ouchi,2 Fumio Kishi,3 Mitsuaki Tabuchi,3 Naoki Tsumura,4 Hisaichi Bannai,5 Satoshi Iwata,6 Toshihiro Tanaka,7 and Mikio Oka1

Division of Respiratory Diseases, Department of Medicine,1 Department of Pediatrics,2 Department of Molecular Genetics, Kawasaki Medical School, Okayama,3 Department of Pediatrics, Kurume University School of Medicine, Fukuoka,4 Department of Medical Technology, School of Health Science, Kyorin University, Tokyo,5 National Hospital Organization Tokyo Medical Center, Tokyo, Japan,6 Division of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, Toronto, Ontario, Canada7

Received 8 March 2008/ Returned for modification 2 April 2008/ Accepted 6 May 2008

To evaluate a newly developed immunochromatographic test (the MySet test) for the detection of Chlamydophila pneumoniae-specific immunoglobulin M antibodies, the results obtained by the MySet test were compared with those obtained by two serological tests. The sensitivity and specificity of the MySet test were 100% and 92.9%, respectively. The MySet test is rapid and simple to use and is thought to be a useful tool for the selection of appropriate antibiotic therapy.

* Corresponding author. Mailing address: Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, 577 Matsushima, Kurashiki City, Okayama 701-0192, Japan. Phone: 81-86-462-1111. Fax: 81-86-464-1041. E-mail: nao{at}med.kawasaki-m.ac.jp

{triangledown} Published ahead of print on 14 May 2008.

Clinical and Vaccine Immunology, July 2008, p. 1128-1131, Vol. 15, No. 7
1071-412X/08/$08.00+0     doi:10.1128/CVI.00085-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





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