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Clinical and Vaccine Immunology, April 2008, p. 732-734, Vol. 15, No. 4
1071-412X/08/$08.00+0     doi:10.1128/CVI.00014-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Prevalence of Hepatitis E Virus Infection in Children in the Northeast of Spain{triangledown}

Maria Buti,1 Pere Plans,2,3 Angela Domínguez,3,4* Rossend Jardi,5 Francisco Rodriguez Frias,5 Rafael Esteban,1 Luis Salleras,3,4 and Antoni Plasencia2

Liver Unit,1 Biochemistry Departament, Hospital Universitario Valle Hebron and CIBER-EHD of Instituto Carlos III, Passeig Vall d'Hebron 119-121, 08035 Barcelona, Spain,5 Directorate of Public Health, Generalitat of Catalonia,2 CIBER Epidemiology and Public Health (CIBERESP), Cr Roc Boronat 81-95, 08005 Barcelona, Spain,3 Department of Public Health, University of Barcelona, Cr Casanovas 143, 08036 Barcelona, Spain4

Received 14 January 2008/ Returned for modification 28 January 2008/ Accepted 18 February 2008

The prevalence of immunoglobulin G (IgG) anti-hepatitis E virus (anti-HEV) antibodies was studied with a representative sample of 1,249 healthy children aged between 6 and 15 years. IgG anti-HEV antibodies were detected in 57 (4.6%) of the 1,249 samples analyzed, suggesting that some children are exposed to HEV in early childhood.

* Corresponding author. Mailing address: Cr Casanovas 143, 08036 Barcelona, Spain. Phone: 34 93 4024566. Fax: 34 93 4029084. E-mail: angela.dominguez{at}ub.edu

{triangledown} Published ahead of print on 5 March 2008.

Clinical and Vaccine Immunology, April 2008, p. 732-734, Vol. 15, No. 4
1071-412X/08/$08.00+0     doi:10.1128/CVI.00014-08
Copyright © 2008, American Society for Microbiology. All Rights Reserved.





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