CVI
Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Other Versions of this Article:
CVI.00364-07v1
15/1/168    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Domínguez, J.
Right arrow Articles by Ausina, V.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Domínguez, J.
Right arrow Articles by Ausina, V.

 Previous Article  |  Next Article 

Clinical and Vaccine Immunology, January 2008, p. 168-171, Vol. 15, No. 1
1071-412X/08/$08.00+0     doi:10.1128/CVI.00364-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Comparison of Two Commercially Available Gamma Interferon Blood Tests for Immunodiagnosis of Tuberculosis{triangledown}

Jose Domínguez,1,3,4* Juan Ruiz-Manzano,2,3,4 Malú De Souza-Galvão,3,5 Irene Latorre,1,3,4 Celia Milà,5 Silvia Blanco,1,3,4 M. Ángeles Jiménez,5 Cristina Prat,1,3,4 Alicia Lacoma,1,3 Neus Altet,5 and Vicente Ausina1,3,4

Servei de Microbiologia,1 Servei de Pneumologia, Hospital Universitari Germans Trias i Pujol, Fundació Institut en Ciències de la Salut Germans Trias i Pujol, Badalona, Spain,2 Universitat Autònoma de Barcelona, Bellaterra, Spain,3 Ciber Enfermedades Respiratorias, Instituto de Salud Carlos III, Badalona, Spain,4 Unidad de Prevención y Control de la Tuberculosis de Barcelona, Barcelona, Spain5

Received 22 August 2007/ Returned for modification 3 October 2007/ Accepted 21 October 2007

We evaluated the T-SPOT.TB and Quantiferon-TB Gold In tube (QFN-G-IT) tests for diagnosing Mycobacterium tuberculosis infection. T-SPOT.TB was more sensitive than QFN-G-IT in diagnosing both active and latent infection. Both gamma interferon tests were unaffected by prior Mycobacterium bovis BCG vaccination. Among children who were not BCG vaccinated but had a positive tuberculin skin test, QFN-G-IT was negative in 53.3% of cases, and T-SPOT.TB was negative in 50% of cases.

* Corresponding author. Mailing address: Servei de Microbiologia, Fundació Institut en Ciències de la Salut Germans Trias i Pujol, Carretera del Canyet s/n, 08916 Badalona, Barcelona, Spain. Phone: 34 93 497 88 94. Fax: 34 93 497 88 95. E-mail: jadominguez.igtp.germanstrias{at}gencat.net

{triangledown} Published ahead of print on 31 October 2007.

Clinical and Vaccine Immunology, January 2008, p. 168-171, Vol. 15, No. 1
1071-412X/08/$08.00+0     doi:10.1128/CVI.00364-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:



Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
Antimicrob. Agents Chemother. Clin. Microbiol. Rev. Infect. Immun.
J. Clin. Microbiol. J. Virol. ALL ASM JOURNALS

Copyright © 2008 by the American Society for Microbiology. All rights reserved.