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Clinical and Vaccine Immunology, September 2007, p. 1228-1230, Vol. 14, No. 9
1071-412X/07/$08.00+0     doi:10.1128/CVI.00233-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Persistence of West Nile Virus-Specific Antibodies in Viremic Blood Donors{triangledown}

Harry E. Prince,1* Leslie H. Tobler,2 Cindy Yeh,1 Nelly Gefter,2 Brian Custer,2 and Michael P. Busch2

Focus Diagnostics, Cypress, California,1 Blood Systems Research Institute, San Francisco, California2

Received 8 June 2007/ Accepted 16 July 2007

We evaluated West Nile virus (WNV) antibody persistence by using follow-up plasma samples from 35 blood donors who made viremic donations in 2005. At 26 to 34 days of follow-up, all of the donors (n = 33) were positive for WNV immunoglobulin M (IgM), IgA, and IgG. At 1-year of follow-up, 17% of the donors (n = 23) were positive for WNV IgM, 57% were positive for WNV IgA, and 100% were positive for WNV IgG.

* Corresponding author. Mailing address: 5785 Corporate Avenue, Cypress, CA 90630. Phone: (714) 503-2047. Fax: (714) 821-3364. E-mail: hprince{at}focusdx.com

{triangledown} Published ahead of print on 25 July 2007.

Clinical and Vaccine Immunology, September 2007, p. 1228-1230, Vol. 14, No. 9
1071-412X/07/$08.00+0     doi:10.1128/CVI.00233-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Prince, H. E., Calma, J., Pham, T., Seaton, B. L. (2009). Frequency of Missed Cases of Probable Acute West Nile Virus (WNV) Infection when Testing for WNV RNA Alone or WNV Immunoglobulin M Alone. CVI 16: 587-588 [Abstract] [Full Text]  


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