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Clinical and Vaccine Immunology, June 2007, p. 799-801, Vol. 14, No. 6
1071-412X/07/$08.00+0     doi:10.1128/CVI.00483-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Evaluation of Two Rapid Immunochromatographic Assays for Diagnosis of Dengue among Vietnamese Febrile Patients{triangledown}

Tran Thi Thanh Nga,1,2 Khoa T. D. Thai,1 Hoang Lan Phuong,1,3 Phan Trong Giao,3 Le Quoc Hung,3 Tran Quang Binh,3 Vo Thi Chi Mai,4 Nguyen Van Nam,5 and Peter J. de Vries1*

Division of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Center F4-217, P.O. Box 22700, 1100 DE Amsterdam, The Netherlands,1 Department of Virology, Cho Ray Hospital, 201 B Nguyen Chi Thanh, District 5, Ho Chi Minh City, Vietnam,2 Department of Tropical Diseases, Cho Ray Hospital, 201 B Nguyen Chi Thanh, District 5, Ho Chi Minh City, Vietnam,3 Department of Microbiology, Cho Ray Hospital, 201 B Nguyen Chi Thanh, District 5, Ho Chi Minh City, Vietnam,4 Binh Thuan Provincial Malaria Center, 133 A Hai Thuong Lan Ong, Phan Thiet City, Vietnam5

Received 27 December 2006/ Returned for modification 5 February 2007/ Accepted 12 April 2007

Results from two dengue rapid tests, the PanBio Duo cassette and the SD Bioline strip test, were compared to those of enzyme-linked immunosorbent assays (Focus Diagnostics) from sera of 200 Vietnamese febrile patients. The PanBio assay was superior, with sensitivity and specificity values for acute-phase serum samples of 54% and 70% (immunoglobulin M) and 70% and 88% (immunoglobulin G), respectively.

* Corresponding author. Mailing address: Division of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Center, F4-217, Meibergdreef 9 1105 AZ Amsterdam, The Netherlands. Phone: 31 20 5664380. Fax: 31 20 6972286. E-mail: p.j.devries{at}amc.uva.nl

{triangledown} Published ahead of print on 25 April 2007.

Clinical and Vaccine Immunology, June 2007, p. 799-801, Vol. 14, No. 6
1071-412X/07/$08.00+0     doi:10.1128/CVI.00483-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.





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