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Clinical and Vaccine Immunology, March 2007, p. 328-330, Vol. 14, No. 3
1071-412X/07/$08.00+0     doi:10.1128/CVI.00349-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Ability of Monocyte-Derived Dendritic Cells To Secrete Oxygen Radicals in Response to Formyl Peptide Receptor Family Agonists Compared to That of Myeloid and Plasmacytoid Dendritic Cells{triangledown}

Anna Karlsson, Erik Nygren,{dagger} Jennie Karlsson, Inger Nordström, Claes Dahlgren, and Kristina Eriksson*

Department of Rheumatology and Inflammation Research, Göteborg University, Göteborg, Sweden

Received 13 September 2006/ Returned for modification 7 November 2006/ Accepted 28 December 2006

We show that human monocyte-derived dendritic cells (DC) differ considerably from freshly isolated blood-derived myeloid and plasmacytoid DC in their abilities to produce reactive oxygen species in response to different agonists to the formyl peptide receptor family and are thus poor representatives of blood DC in this field of research.

* Corresponding author. Mailing address: Department of Rheumatology and Inflammation Research, Guldhedsgatan 10A, 413 46 Göteborg, Sweden. Phone: 46-31-3424761. Fax: 46-31-823925. E-mail: Kristina.Eriksson{at}microbio.gu.se.

{triangledown} Published ahead of print on 10 January 2007.

{dagger} Present address: Department of Microbiology and Immunology, Göteborg University, Göteborg, Sweden.

Clinical and Vaccine Immunology, March 2007, p. 328-330, Vol. 14, No. 3
1071-412X/07/$08.00+0     doi:10.1128/CVI.00349-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.





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