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Clinical and Vaccine Immunology, November 2007, p. 1529-1531, Vol. 14, No. 11
1071-412X/07/$08.00+0     doi:10.1128/CVI.00197-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.

Use of Antigens Derived from Burkholderia pseudomallei, B. thailandensis, and B. cepacia in the Indirect Hemagglutination Assay for Melioidosis{triangledown}

Glenda Gilmore,1 Jodie Barnes,2 Natkunam Ketheesan,2,3 and Robert Norton1,3*

Queensland Health Pathology Services, Townsville Hospital, Townsville, Australia, 4814,1 School of Veterinary and Biomedical Sciences, James Cook University, Townsville, Australia 4814,2 School of Medicine, James Cook University, Townsville, Australia 48143

Received 9 May 2007/ Returned for modification 29 June 2007/ Accepted 25 August 2007

The serological diagnosis of melioidosis is carried out using the indirect hemagglutination assay. We looked at the reactivity of sera from culture-proven cases of melioidosis from north Queensland against antigens derived from Burkholderia pseudomallei, B. thailandensis, and B. cepacia. Cross-reactivity between sera from culture-positive cases of melioidosis and B. thailandensis was demonstrated.

* Corresponding author. Mailing address: Department of Clinical Microbiology, QHPS, Townsville Hospital, Townsville, Qld 4814, Australia. Phone: 61 (07) 47 961111. Fax: 61 (07) 47 962415. E-mail: Robert_Norton{at}health.qld.gov.au

{triangledown} Published ahead of print on 5 September 2007.

Clinical and Vaccine Immunology, November 2007, p. 1529-1531, Vol. 14, No. 11
1071-412X/07/$08.00+0     doi:10.1128/CVI.00197-07
Copyright © 2007, American Society for Microbiology. All Rights Reserved.



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