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Seroincidence of Recent Human Immunodeficiency Virus Type 1 Infections in China

National AIDS Reference Laboratory, National Center for AIDS & STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, People's Republic of China,¹ Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama 35294-0022,² Institute for Global Health and Department of Pediatrics, School of Medicine, Vanderbilt University, Nashville, Tennessee 37232-0242³

Received 18 September 2006/ Returned for modification 13 March 2007/ Accepted 25 July 2007

A subtype B, E, and D immunoglobulin G capture immunoassay shows promise as a tool for estimating human immunodeficiency virus type 1 seroincidence from cross-sectional surveys, but the test-specific limitations suggest that an adjustment is necessary, and further validation of the assay with populations with divergent subtypes is needed.

Published ahead of print on 1 August 2007.

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