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Clinical and Vaccine Immunology, June 2006, p. 702-703, Vol. 13, No. 6
1071-412X/06/$08.00+0     doi:10.1128/CVI.00194-05
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Poor Performance of a Novel Serological Test for Diagnosis of Pulmonary Tuberculosis in Bangui, Central African Republic

Eric Kassa-Kelembho,1,{dagger} Edith Kassa,1 Germain Zandanga,1 Yves-Brillant Service,2 Albert Ignaleamoko,3 and Antoine Talarmin1*

Institut Pasteur de Bangui,1 Department of Medicine, Hôpital Communautaire,2 Chest Clinic, National Teaching Hospital, Bangui, Central African Republic3

Received 28 June 2005/ Returned for modification 19 September 2005/ Accepted 22 March 2006

We assessed the performance of a serological test for tuberculosis (SDHO Laboratories Inc., Canada) in our setting. Among 68 of 99 suspected pulmonary tuberculosis patients who were scored as having tuberculosis on the basis of Mycobacterium tuberculosis-positive culture, the sensitivity of the serological test was lower than that of sputum smear microscopic examination (20.6% versus 80.9%, respectively; P < 0.000001).

* Corresponding author. Present address: Institut Pasteur de Madagascar, BP 1274, Antananarivo 101, Madagascar. Phone: (261 20) 22 412 72. Fax: (261 20) 22 415 34. E-mail: atalarmin{at}pasteur.mg.

{dagger} Deceased

Clinical and Vaccine Immunology, June 2006, p. 702-703, Vol. 13, No. 6
1071-412X/06/$08.00+0     doi:10.1128/CVI.00194-05
Copyright © 2006, American Society for Microbiology. All Rights Reserved.





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