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Clinical and Vaccine Immunology, March 2006, p. 329-332, Vol. 13, No. 3
1071-412X/06/$08.00+0     doi:10.1128/CVI.13.3.329-332.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Recognizing Primary Immune Deficiency in Clinical Practice

Hale Yarmohammadi,1* Lissette Estrella,1 John Doucette,2 and Charlotte Cunningham-Rundles1

Departments of Medicine and Pediatrics,1 Department of Community & Preventive Medicine, The Mount Sinai Medical Center, New York, New York2

Received 13 July 2005/ Returned for modification 2 September 2005/ Accepted 5 December 2005

Primary immunodeficiency results in recurrent infections, organ dysfunction, and autoimmunity. We studied 237 patients referred for suspicion of immunodeficiency, using a scoring system based on clinical information. The 113 patients with immunodeficiency had higher scores and more episodes of chronic illnesses and were more likely to have neutropenia, lymphopenia, or splenomegaly.

* Corresponding author. Mailing address: Division of Clinical Immunology, Mount Sinai Medical Center, 1425 Madison Ave., New York, NY 10029. Phone: (212) 659-9261. Fax: (212) 987-5593. E-mail: hale.yar{at}mssm.edu.

Clinical and Vaccine Immunology, March 2006, p. 329-332, Vol. 13, No. 3
1071-412X/06/$08.00+0     doi:10.1128/CVI.13.3.329-332.2006
Copyright © 2006, American Society for Microbiology. All Rights Reserved.





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