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Clinical and Diagnostic Laboratory Immunology, September 2005, p. 1117-1118, Vol. 12, No. 9
1071-412X/05/$08.00+0     doi:10.1128/CDLI.12.9.1117-1118.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Human Immunodeficiency Virus Infection and Levels of Dehydroepiandrosterone Sulfate in Plasma among Indians

A. J. Kandathil,1 R. Kannangai,1 S. David,1 R. Selvakumar,2 V. Job,2 O. C. Abraham,3 and G. Sridharan1*

Departments of Clinical Virology,1 Clinical Biochemistry,2 Internal Medicine (Unit 1), Christian Medical College, Vellore, Tamil Nadu, India 6320043

Received 30 May 2005/ Returned for modification 10 June 2005/ Accepted 16 June 2005

The shift in cytokine profile during human immunodeficiency virus (HIV) disease progression is influenced by dehydroepiandrosterone sulfate (DHEAS) level. Radioimmunoassay was used to measure plasma DHEAS for 30 treatment-naïve HIV-infected and 30 uninfected individuals. There was a significant negative correlation of viral load with DHEAS level (P < 0.05). Further studies of the use of DHEAS levels for monitoring HIV patients economically are warranted.

* Corresponding author. Mailing address: Department of Clinical Virology, Christian Medical College, Vellore, India 632004. Phone: 91 (416) 228 2070. Fax: 91 (416) 223 2035. E-mail: g_sridharan{at}yahoo.com.

Clinical and Diagnostic Laboratory Immunology, September 2005, p. 1117-1118, Vol. 12, No. 9
1071-412X/05/$08.00+0     doi:10.1128/CDLI.12.9.1117-1118.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.





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