This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Seet, R. C. S.
Right arrow Articles by Tambyah, P. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Seet, R. C. S.
Right arrow Articles by Tambyah, P. A.

 Previous Article  |  Next Article 

Clinical and Diagnostic Laboratory Immunology, May 2005, p. 680-682, Vol. 12, No. 5
1071-412X/05/$08.00+0     doi:10.1128/CDLI.12.5.680-682.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Strongyloides Hyperinfection and Hypogammaglobulinemia

Raymond C. S. Seet,1* Lee Gong Lau,2 and Paul Ananth Tambyah1

Department of Medicine,1 Department of Hematology-Oncology, National University Hospital, Singapore2

Received 6 January 2005/ Returned for modification 15 February 2005/ Accepted 23 February 2005

We report strongyloides hyperinfection in two patients with generalized hypogammaglobulinemia from multiple myeloma and nephrotic syndrome, despite a significant strongyloides-specific immunoglobulin G (IgG) response. In contrast to reports on animals, where human IgG was shown to be a protective antibody, our observation suggests that in humans, immunity to the infective-stage larvae is not protective against the autoinfective larvae, which are the causative agents of strongyloides hyperinfection.

* Corresponding author. Mailing address: Department of Medicine, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074. Phone: 65-67792516. Fax: 65-67794112. E-mail: raymond_seet{at}nus.edu.sg.

Clinical and Diagnostic Laboratory Immunology, May 2005, p. 680-682, Vol. 12, No. 5
1071-412X/05/$08.00+0     doi:10.1128/CDLI.12.5.680-682.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Page, K. R., Zenilman, J. (2008). Eosinophilia in a Patient From South America. JAMA 299: 437-444 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»