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Clinical and Diagnostic Laboratory Immunology, November 2004, p. 1189-1191, Vol. 11, No. 6
1071-412X/04/$08.00+0     DOI: 10.1128/CDLI.11.6.1189-1191.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Expression of Tocopherol-Associated Protein in Mast Cells

Teruo Ikeda,1 Masaru Murakami,2 and Masayuki Funaba3*

Azabu University Research Institute of Biosciences,1 Molecular Biology,2 Nutrition, Azabu University School of Veterinary Medicine, Sagamihara, Japan3

Received 19 May 2004/ Accepted 23 July 2004

Tocopherol-associated protein (TAP) was expressed in mouse mast cells. TAP was predominantly localized in the cytoplasm, and the subcellular localization was not changed by {alpha}-tocopherol. The results suggest that the physiological role of TAP in mast cells is not regulation of tocopherol function but an as-yet-unidentified activity.


* Corresponding author. Mailing address: Laboratory of Nutrition, Azabu University School of Veterinary Medicine, 1-17-71 Fuchinobe, Sagamihara 229-8501, Japan. Phone: 81-42-754-7111(276). Fax: 81-42-754-9930. E-mail: funaba{at}azabu-u.ac.jp.


Clinical and Diagnostic Laboratory Immunology, November 2004, p. 1189-1191, Vol. 11, No. 6
1071-412X/04/$08.00+0     DOI: 10.1128/CDLI.11.6.1189-1191.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.