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Clinical and Diagnostic Laboratory Immunology, July 2004, p. 789-791, Vol. 11, No. 4
1071-412X/04/$08.00+0     DOI: 10.1128/CDLI.11.4.789-791.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Impact of Serological Methodology on Assessment of the Link between Chlamydia pneumoniae and Vascular Diseases

Regional Laboratory for Medical Microbiology, Dordrecht,¹ Department of Endocrinology and Department of Epidemiology and Biostatistics, University Medical Center, Nijmegen,² Department of Clinical Microbiology, Amphia Hospital, Breda,³ Department of Clinical Microbiology, St. Elisabeth Hospital, Tilburg, The Netherlands⁴

Received 18 November 2003/ Returned for modification 13 January 2004/ Accepted 24 March 2004

We assessed the impact of five serologic tests on the link between Chlamydia pneumoniae and abdominal aortic aneurysms (AAA). The results of the tests were inconsistent. Agreement among the five tests was generally poor. Detection of the link between C. pneumoniae and AAA depends on the serologic methodology chosen.

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