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Clinical and Diagnostic Laboratory Immunology, May 2004, p. 618-620, Vol. 11, No. 3
1071-412X/04/$08.00+0     DOI: 10.1128/CDLI.11.3.618-620.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Evaluation of Commercial Immunoassays for Detection of Antibody against Helicobacter pylori in Thai Dyspeptic Patients

Orrawadee Hanvivatvong,1* Atinop Pongpanich,1 Duangporn Thong-Ngam,2 Niramol Thammacharoenrach,1 and Pinit Kullavanijaya3

Department of Microbiology,1 Department of Physiology,2 Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand3

Received 16 October 2003/ Returned for modification 12 December 2003/ Accepted 12 February 2004

The performance of five immunoassays for detection of immunoglobulin G antibody against Helicobacter pylori in 191 dyspeptic patients was evaluated. The sensitivities, specificities, accuracies, positive predictive values, and negative predictive values ranged from 86.32 to 97.89%, 57.95 to 72.22%, 77.02 to 83.76%, 71.54 to 77.42%, and 83.33 to 96.23%, respectively. The immunoglobulin A test kit also gave a high sensitivity and negative predictive value (95.79 and 91.40%, respectively), while the specificity was relatively low (51.14%).

* Corresponding author. Mailing address: Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand. Phone: 662 252 8181-3666. Fax: 662 252 5952. E-mail: fmedohv{at}md2.md.chula.ac.th.

Clinical and Diagnostic Laboratory Immunology, May 2004, p. 618-620, Vol. 11, No. 3
1071-412X/04/$08.00+0     DOI: 10.1128/CDLI.11.3.618-620.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.





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